Effects of alveolar dead-space, shunt andV˙/Q˙distribution on respiratory dead-space measurements

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Effects of alveolar dead-space, shunt and V/Q distribution on respiratory dead-space measurements.

BACKGROUND Respiratory dead-space is often increased in lung disease. This study evaluates the effects of increased alveolar dead-space (Vd(alv)), pulmonary shunt, and abnormal ventilation perfusion ratio (/) distributions on dead-space and alveolar partial pressure of carbon dioxide (Pa(co(2))) calculated by various methods, assesses a recently published non-invasive method (Koulouris method) ...

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RESPIRATION AND THE AIRWAY Effects of alveolar dead - space , shunt and _ V = _ Q distribution on respiratory dead - space measurements

Background. Respiratory dead-space is often increased in lung disease. This study evaluates the effects of increased alveolar dead-space (VDalv), pulmonary shunt, and abnormal ventilation perfusion ratio ( _ V= _ Q) distributions on dead-space and alveolar partial pressure of carbon dioxide (PACO2) calculated by various methods, assesses a recently published non-invasive method (Koulouris metho...

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Alveolar dead-space response to activated protein C in acute respiratory distress syndrome.

We report a complicated case of acute respiratory distress syndrome (ARDS) from severe sepsis, in which we measured the ratio of physiologic dead space to tidal volume (V(D)/V(T)) with volumetric capnography prior to, during, and after therapy with human recombinant activated protein C. Previous studies hypothesized that early in ARDS, elevated V(D)/V(T) primarily reflects increased alveolar V(...

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Alveolar Dead Space Fraction Discriminates Mortality in Pediatric Acute Respiratory Distress Syndrome.

OBJECTIVES Physiologic dead space is associated with mortality in acute respiratory distress syndrome, but its measurement is cumbersome. Alveolar dead space fraction relies on the difference between arterial and end-tidal carbon dioxide (alveolar dead space fraction = (PaCO2 - PetCO2) / PaCO2). We aimed to assess the relationship between alveolar dead space fraction and mortality in a cohort o...

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Dead space: simplicity to complexity.

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ژورنال

عنوان ژورنال: British Journal of Anaesthesia

سال: 2005

ISSN: 0007-0912

DOI: 10.1093/bja/aei212